| Pair Name | Secoisolariciresinol, Doxorubicin | ||
| Phytochemical Name | Secoisolariciresinol (PubChem CID: 65373 ) | ||
| Anticancer drug Name | Doxorubicin (PubChem CID: 31703 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Secoisolariciresinol, Doxorubicin | |||
| Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
| Biological Phenomena | Induction-->P-gp inhibitor | |||
| In Vitro Model | NCI-ADR-RES | High grade ovarian serous adenocarcinoma | Homo sapiens (Human) | CVCL_1452 |
| Result | Our results suggest SECO as a novel P-gp inhibitor that can re-sensitize cancer cells during DOX chemotherapy. | |||
| No. | Title | Href |
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| 1 | In silico and in vitro identification of secoisolariciresinol as a re-sensitizer of P-glycoprotein-dependent doxorubicin-resistance NCI/ADR-RES cancer cells. PeerJ. 2020 Jun 10;8:e9163. doi: 10.7717/peerj.9163. | Click |
